Canada Research Chair in Computational Cancer Genomics
Sohrab Shah, an Assistant Professor in the Department of Pathology & Laboratory Medicine, is at the forefront of applying new cancer genome sequencing technologies to gain insight into the genetic underpinnings of disease, and he uses computational innovations to model the evolutionary and biological properties of cancer genomes. His team has published several high-impact studies, and most recently described the dramatic extent of intratumoural heterogeneity in high grade serous ovarian cancers at the time of surgical staging. He is extremely excited about the opportunity to profile tumour evolution at the resolution of single cells in order to precisely determine the genetic properties of tumour progression, metastases, and therapeutic resistance.