Canada Research Chair in Genetic Epidemiology of Common Complex Diseases
Dr. Denise Daley, an Associate Professor in the Department of Medicine, is leading one of six Canadian teams participating in the International Epigenome Project.
She is utilizing cutting-edge statistical, epigenetic, and bioinformatics techniques to obtain a better understanding of how inherited genetic variants and environmental exposures interact to modify the risk for developing disease. Her lab is working with a number of common complex diseases including asthma and allergic disease, COPD, cardiovascular disease, and cancer. Her lab was the first to establish that the thymic stromal lymphopoietin gene is associated with the development of asthma and allergic disease, a finding that was subsequently replicated by numerous labs and studies around the world. Dr. Daley is very excited about the potential to utilize these advancements to better understand the etiology of disease and the modifiable environmental risk factors to identify individuals at greatest risk and to develop biomarkers and public health interventions.