Faculty of Medicine researchers receive CIHR grants

Brian MacVicar, Professor, Department of Psychiatry received the largest grant in CIHR's latest round of awards.

Brian MacVicar, Professor, Department of Psychiatry received the largest grant in the Faculty from CIHR’s latest round of awards.

The Canadian Institutes for Health Research has announced its latest grants, and 58 members of the Faculty of Medicine are among the awardees. Grant recipients were chosen through a rigorous peer-review process.

The UBC Faculty of Medicine recipients and their project titles are:

Samuel Aparicio, Professor in the Department of Pathology and Laboratory Medicine
Targeting the dynamics and genomics of clonal evolution in cancer patients, $2.8M for 7 years

Francois Benard, Professor in the Department of Radiology
Lipid nanomedicines for health and disease, $1.4M for 7 years

Pieter Cullis, Professor in the Department of Biochemistry & Molecular Biology
Targeted radiopharmaceuticals to improve cancer diagnosis and treatment, $2.1M for 7 years

Kurt Haas, Professor in the Department of Cellular & Physiological Sciences
Imaging neural circuit dynamics in the awake developing brain: Identifying origins of neurodevelopmental disorders, $3.2M for 7 years

Philip A Hieter, Professor in the Department of Medical Genetics
Chromosome instability and synthetic lethality in yeast, $2.5M for 7 years

Corinne Hohl, Associate Professor in the Department of Emergency Medicine
When Treatments Harm: Building Better Systems and Enhancing Research Capacity to Reduce Adverse Drug Events, $1.1M for 5 years

Christian J Kastrup, Assistant Professor in the Department of Biochemistry and Molecular Biology
Materials and Mechanisms for Understanding and Controlling Hemorrhage, $1.4M for 5 years

Thomas H Kerr, Professor in the Department of Medicine
Improving healthcare and health outcomes among people who use drugs in Canada, $1.3M for 7 years

Michael R Law, Associate Professor in the School of Population and Public Health
Improving Access to Medicines in Canada and Abroad, $2.3M for 7 years

Brian MacVicar, Professor in the Department of Psychiatry
Neuron-Glia interactions in brain disease, $3.3M for 7 years

Martin T Schechter, Professor in the School of Population and Public Health
Reducing HIV risk, increasing access to treatment and promoting resilience in Indigenous communities in Canada and globally, $1.6M for 7 years

Christian Steidl, Assistant Professor in the Department of Pathology and Laboratory Medicine
The biology and clinical significance of the tumour microenvironment in B cell lymphomas, $1.5M for 5 years

Nobuhiko Tokuriki, Assistant Professor in the Department of Biochemistry and Molecular Biology
Evolutionary approaches to treat and evade antibiotic resistant pathogenic bacteria, , $1.1M for 5 years

The UBC Faculty of Medicine recipients and their project titles are:

Douglas W Allan, Assistant Professor in the Department of Cellular & Physiological Sciences
Characterization of the genes and gene regulatory mechanisms that control motor neuron stability and neurotransmission in a Drosophila model, $745K for 5 years

Yossef Av-Gay, Professor in the Department of Medicine (Infectious Diseases)
Intracellular growth of Mycobacterium tuberculosis: Prospects for drug discovery, $803K for 5 years

Shernaz Bamji, Associate Professor in the Department of Cellular & Physiological Sciences
The Palmitoyl Acyl Transferase, DHHC5, in Neural Circuit Development and Function, $820K for 5 years

Peter Black, Assistant Professor in the Department of Urologic Sciences
Early clinical testing of intravesical administration of the muco-adherent, docetaxel-laden polymer STK-01 in bladder cancer, $321K for 3 years

Michael E Cox, Associate Professor in the Department of Urologic Sciences
Development of targeted therapeutics for ERG-expressing prostate cancers, $910K for 5 years

Brett Finlay, Professor in the Department of Biochemistry and Molecular Biology
Malnutrition and the Microbiota, 680K for 5 years
The Role of the Microbiota in Asthma, $780K for 5 years

Francis A Gordon, Professor in the Department of Medicine
The unrecognized importance of smooth muscle foam cells in atherosclerosis development and treatment, $740K for 5 years

Roxana Geoffrion, Assistant Professor in the Department of Obstetrics & Gynaecology
Vaginal Surgery for the Pelvic Floor: A Randomized Trial of Synthetic Mesh Versus Synthetic Sutures, $573K for 5 years

William T Gibson, Associate Professor in the Department of Medical Genetics
Insights from Rare Overgrowth Syndromes for Common Diseases, $275K for 3 years
Regulation of islet cell proliferation by p300, $245K for 3 years

Eric Jan, Associate Professor in the Department of Biochemistry & Molecular Biology
Translation reading frame selection directed by a viral internal ribosome entry site, $868K for 5 years

Wilfred Jefferies, Professor in the Departments of Microbiology and Immunology and Medical Genetics
Studies on novel immune-surveillance mechanisms underlying cancer elimination, $880K for 5 years

Jayachandran Kizhakkedathu , Associate Professor in the Department of Pathology and Laboratory Medicine
Novel One-step Approach to a Universal Anti-adhesion Coating to Prevent Catheter-associated Urinary Tract Infections, $187K for 1.6 years

Michael Kobor, Associate Professor in the Department of Medical Genetics
Epigenetic Signatures of Successful Aging, $1.1M for 5 years

Vivian D Lima, Assistant Professor in the Department of Medicine (HIV/AIDS)
The Health and Economic Forecasting Micro-Simulation Model: A tool to evaluate future health policies and programmatic interventions targeting the aging population living with HIV in British Columbia, $558K for 5 years

Teresa Liu-Ambrose, Associate Professor in the Department of Physical Therapy
One size does not fit all: Tailoring exercise prescription for brain health based on BDNF polymorphism, $1.1M for 5 years

William W Lockwood, Professor in the Department of Pathology & Laboratory Medicine
Developing agonistic therapeutic strategies for lung cancer based on synthetic lethal oncogene interactions, $765K for 5 years

Thibault Mayor, Associate Professor in the Department of Biochemistry & Molecular Biology
Characterization of the proteostasis decline upon aging, $669K for 5 years

Kimberlyn Mcgrail, Associate Professor in the School of Population and Public Health
Filling the void: Public engagement around a new model for access to research resources, $405K for 3 years

Kelly McNagny, Professor in the Department of Medical Genetics
Innate Lymphoid cells and RAR-related orphan receptor alpha (RORa) as therapeutic targets for gastrointestinal fibrosis and Crohn's disease, $760K for 5 years

William Miller, Professor in the Department of Occupational Science and Occupational Therapy
Feasibility of the Hip Instructional Prehabilitation Program for Enhanced Recovery (HIPPER) intervention protocol: an eHealth approach for pre-surgical hip replacement education, $225K for 2 years

Robert Molday, Professor in the Department of Biochemistry & Molecular Biology
Molecular Mechanisms and Therapeutic Approaches to Stargardt Macular Degeneration, $1.1M for 5 years

Edwin Moore, Professor in the Department of Cellular & Physiological Sciences
Cardiac Excitation-Contraction Coupling: The Dynamic Dyad, $993K for 5 years

Ivan Nabi, Professor in the Department of Cellular & Physiological Sciences
Control of ER-mitochondria contacts and mitophagy by the Gp78 ubiquitin ligase: Role in tumor progression, $1.1M for 5 years

Catherine J Pallen, Professor in the Department of Pediatrics
PTP Alpha in Normal and Tumor Cell Motility, $719K for 5 years

Calvin Roskelley, Professor in the Department of Cellular & Physiological Sciences
The role of hyaluronan in priming and populating the inflammatory micrometastatic niche, $623K for 5 years

Ivan J Sadowski, Professor in the Department of Biochemistry & Molecular Biology
Modulation of HIV provirus expression to eliminate latently infected cells, $726K for 5 years

Jean Shoveller, Professor in the School of Population and Public Health
Socio-cultural Contexts and Young Men's Sexual Lives, $573K for 5 years

Patricia Spittal, Professor in the School of Population and Public Health
The Cedar Project: Providing culturally-safe, strengths-based case management for the delivery of optimal hepatitis C care and treatment among Indigenous people who use drugs in Vancouver and Prince George, British Columbia, $1.1M for 3 years

John A Staples, Clinical Assistant Professor in the Department of Medicine (General Internal Medicine)
Syncope and the subsequent risk of motor vehicle crash: A population-based analysis, $180K for 3 years

Michael Underhill, Associate Professor in the Department Cellular & Physiological Sciences
Defining Activated Stromal Signatures and Targeting the Tumour Microenvironment of Pancreatic Ductal Adenocarcinoma, $677K for 5 years
Tissue-resident mesenchymal progenitors and aging, $833 for 5 years

Filip Van Petegem, Associate Professor in the Department of Biochemistry & Molecular Biology
Structural and functional investigation of arrhythmia-associated mutations in calmodulin, $733K for 5 years

Bruce A Vallance, Associate Professor in the Department of Pediatrics
Colonic Goblet Cells: Active Players in Host Defense and Mucosal Protection?, $210K for 5 years

Yu Tian Wang, Professor in the Department of Medicine
Developing novel GluN2A-containing NMDAR-based stroke therapies, $956K for 5 years

Andrew P Weng, Associate Professor in the Department of Pathology & Laboratory Medicine
Mediators and targets of Wnt signaling in T-ALL stem cells, $841K for 5 years
Resolution of inter- and intra-tumoral heterogeneity in DLBCL using mass cytometry, $860 for 5 years

David R Wilson, Professor in the Department of Orthopedics
Development and Validation of a New Method for Measuring Cartilage Load Using Upright Open MRI, $474K for 4 years

Haishan Zeng, Professor in the Department of Dermatology & Skin Science
Improving Periphery Lung Cancer Detection by Endoscopic Laser Raman Spectroscopy, $520K for 4.6 years

Each recipient of the award receives $300,000 over five years.

Liam Brunham, Assistant Professor in the Department of Medicine
Cardiovascular Genetics: Phenotypes, Genotypes and Cellular Mechanisms

Janel Kopp, Assistant Professor in the Department of Cellular & Physiological Sciences
Molecular And Cellular Mechanisms Leading To Pancreatic Cancer Heterogeneity

Dirk Lange, Assistant Professor in the Department of Urologic Sciences
The Development of Novel Therapeutic and Preventative Strategies for Kidney Stone Disease

Ryan McNeil, Assistant Professor in the Department of Medicine
A Research Program to Ensure the Effective Delivery of Substance Use Treatment Across Acute and Community Care Settings

Michael-John Milloy, Assistant Professor in the Department of Medicine
Investigating pathogenesis of blood-borne infections among people who use illicit drugs

William Mortenson, Assistant Professor in the Occupational Science and Occupational Therapy
Maximizing Independence through the Use of Assistive Technology

Mohsen Sadatsafavi, Assistant Professor in the Department of Medicine
Respiratory Evaluation Sciences Program (RESP): Innovations in analytic approaches to improve efficiency in respiratory care

Jill Zwicker, Assistant Professor in the Occupational Science and Occupational Therapy
Developmental Coordination Disorder: Integrating Brain Imaging and Rehabilitation to Improve Outcomes

Gillian Hanley, Assistant Professor in the Occupational Science and Occupational Therapy
Using 'big data' to improve women's health: Population based research in ovarian cancer and healthy reproduction